ID   TC-138
AC   CVCL_4Z30
SY   TC138
DR   Cell_Model_Passport; SIDM01467
DR   Cosmic; 2228236
DR   DepMap; ACH-001430
DR   Wikidata; Q54971795
RX   PubMed=25010205;
WW   https://www.cccells.org/tables/Ewings.php
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=25010205).
CC   Sequence variation: Gene fusion; HGNC; 3508; EWSR1 + HGNC; 3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 4 fusion (Ex10/Ex5) (PubMed=25010205).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=25010205
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 8,10
ST   D16S539: 10
ST   D18S51: 13,14
ST   D19S433: 13,14
ST   D21S11: 29
ST   D2S1338: 17,23
ST   D3S1358: 16,18
ST   D5S818: 12
ST   D7S820: 9,11
ST   D8S1179: 10
ST   FGA: 22
ST   TH01: 7,9
ST   TPOX: 11
ST   vWA: 19
DI   NCIt; C27291; Ewing sarcoma/peripheral primitive neuroectodermal tumor
DI   ORDO; Orphanet_223727; Bone sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 05-10-23; Version: 10
//
RX   PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782;
RA   Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S.,
RA   Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y.,
RA   Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H.,
RA   Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S.,
RA   Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.;
RT   "The genomic landscape of the Ewing sarcoma family of tumors reveals
RT   recurrent STAG2 mutation.";
RL   PLoS Genet. 10:E1004475-E1004475(2014).
//