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Cellosaurus UKF-Rhb-1 (CVCL_4Z17)

[Text version]
Cell line name UKF-Rhb-1
Accession CVCL_4Z17
Resource Identification Initiative To cite this cell line use: UKF-Rhb-1 (RRID:CVCL_4Z17)
Comments Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Alveolar rhabdomyosarcoma (NCIt: C3749)
Alveolar rhabdomyosarcoma (ORDO: Orphanet_99756)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RQ48 (UKF-Rhb-1rCDDP1000)CVCL_RQ49 (UKF-Rhb-1rDOCE10)CVCL_RT27 (UKF-Rhb-1rDOCE20)
CVCL_RQ56 (UKF-Rhb-1rDOX10)CVCL_RT28 (UKF-Rhb-1rDOX20)CVCL_RQ57 (UKF-Rhb-1rGEMCI10)
CVCL_RQ58 (UKF-Rhb-1rIRINO200)CVCL_RQ59 (UKF-Rhb-1rMEL400)CVCL_RS17 (UKF-Rhb-1rNutlin10muM)
CVCL_RQ60 (UKF-Rhb-1rOXALI1000)CVCL_4Z18 (UKF-Rhb-1rVCR10)
Category Cancer cell line
Publications

PubMed=19147553; DOI=10.1158/0008-5472.CAN-08-1856
Michaelis M., Rothweiler F., Klassert D., von Deimling A., Weber K., Fehse B., Kammerer B., Doerr H.-W., Cinatl J. Jr.
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Cancer Res. 69:416-421(2009)

PubMed=22170099; DOI=10.1038/cddis.2011.129; PMCID=PMC3252738
Michaelis M., Rothweiler F., Barth S., Cinatl J., van Rikxoort M., Loschmann N., Voges Y., Breitling R., von Deimling A., Rodel F., Weber K., Fehse B., Mack E., Stiewe T., Doerr H.-W., Speidel D., Cinatl J. Jr.
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.
Cell Death Dis. 2:e243.1-e243.8(2011)

PubMed=23665679; DOI=10.1038/onc.2013.129
Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

Cross-references
Encyclopedic resources Wikidata; Q54990406
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number8