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Cellosaurus PG19T3:MTXR10-4M (CVCL_4Y71)

[Text version]
Cell line name PG19T3:MTXR10-4M
Synonyms PG19T3:MTXR.10-4 M
Accession CVCL_4Y71
Resource Identification Initiative To cite this cell line use: PG19T3:MTXR10-4M (RRID:CVCL_4Y71)
Comments Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J.
Hierarchy Parent: CVCL_S407 (PG19T3)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=510081; DOI=10.1007/BF00292270
Bostock C.J., Clark E.M., Harding N.G.L., Mounts P.M., Tyler-Smith C., van Heyningen V., Walker P.M.B.
The development of resistance to methotrexate in a mouse melanoma cell line. I. Characterisation of the dihydrofolate reductases and chromosomes in sensitive and resistant cells.
Chromosoma 74:153-177(1979)

Cross-references
Encyclopedic resources Wikidata; Q54947320
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number4