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Cellosaurus CA-CD437R (CVCL_4Y66)

[Text version]
Cell line name CA-CD437R
Accession CVCL_4Y66
Resource Identification Initiative To cite this cell line use: CA-CD437R (RRID:CVCL_4Y66)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:88334; AHPN (6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalenecarboxylic acid; CD437).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136Ter (c.406C>T); ClinVar=VCV001802458; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0201 (Caov-3)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=12237293; DOI=10.1074/jbc.M204600200
Holmes W.F., Soprano D.R., Soprano K.J.
Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line.
J. Biol. Chem. 277:45408-45419(2002)

Cross-references
Encyclopedic resources Wikidata; Q54808292
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number8