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Cellosaurus MCF-7 clone 33 (CVCL_4Y65)

[Text version]
Cell line name MCF-7 clone 33
Accession CVCL_4Y65
Resource Identification Initiative To cite this cell line use: MCF-7 clone 33 (RRID:CVCL_4Y65)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Children:
CVCL_4Y63 (MCF-7/TMX2)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=2055945; DOI=10.1002/jcb.240450209
Gierthy J.F., Lincoln D.W. II, Roth K.E., Bowser S.S., Bennett J.A., Bradley L., Dickerman H.W.
Estrogen-stimulation of postconfluent cell accumulation and foci formation of human MCF-7 breast cancer cells.
J. Cell. Biochem. 45:177-187(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Y65
Encyclopedic resources Wikidata; Q54904306
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number13