Cellosaurus cell line KP-1NL-Luc#2 (CVCL

Cross-references
Cell line name	KP-1NL-Luc#2
Synonyms	KP-1-NL-Luc#2
Accession	CVCL_4Y21
Resource Identification Initiative	To cite this cell line use: KP-1NL-Luc#2 (RRID:CVCL_4Y21)
Comments	Problematic cell line: Contaminated. Grand-parent cell line (KP-1N) has been shown to be a PANC-1 derivative. Population: Caucasian. Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_3003 (KP-1NL)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Cell line collections (Providers)	JCRB; NIHS0714 - Discontinued
Cell line databases/resources	cancercelllines; CVCL_4Y21
Encyclopedic resources	Wikidata; Q54900358
Entry history
Entry creation	14-Dec-2015
Last entry update	10-Sep-2024
Version number	16