Cell line name |
BT-474/CMV-Luc |
Accession |
CVCL_4Y08 |
Resource Identification Initiative |
To cite this cell line use: BT-474/CMV-Luc (RRID:CVCL_4Y08) |
Comments |
Population: Caucasian. Characteristics: Expression of luciferase is under the control of the CMV promoter (JCRB=JCRB1450). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Breast; UBERON=UBERON_0000310. |
Sequence variations |
- Gene fusion; HGNC; HGNC:24618; AHCTF1 + HGNC; HGNC:736; NAAA; Name(s)=AHCTF1-NAAA (from parent cell line).
- Gene fusion; HGNC; HGNC:7609; MYO9B + HGNC; HGNC:9764; RAB22A; Name(s)=RAB22A-MYO9B (from parent cell line).
- Gene fusion; HGNC; HGNC:16173; DOK5 + HGNC; HGNC:17579; STARD3; Name(s)=STARD3-DOK5 (from parent cell line).
- Gene fusion; HGNC; HGNC:16651; MRPL45 + HGNC; HGNC:16181; TRPC4AP; Name(s)=TRPC4AP-MRPL45 (from parent cell line).
- Gene fusion; HGNC; HGNC:13178; IKZF3 + HGNC; HGNC:12649; VAPB; Name(s)=VAPB-IKZF3 (from parent cell line).
- Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ser3094Ter (c.9281C>A); ClinVar=VCV000188440; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11621; HNF1A; Simple; p.Gln495Ter (c.1483C>T); ClinVar=VCV000586785; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6871; MAPK1; Simple; p.His61Gln (c.183C>G); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Lys111Asn (c.333G>C); ClinVar=VCV000376483; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu285Lys (c.853G>A); ClinVar=VCV000420133; Zygosity=Homozygous (from parent cell line).
|
Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0179 (BT-474) |
Sex of cell |
Female |
Age at sampling |
60Y |
Category |
Cancer cell line |
STR profile |
Source(s): JCRB=JCRB1450
Markers: Run an STR similarity search on this cell line |
Cross-references |
Cell line collections (Providers) |
JCRB; JCRB1450
JCRB; NIHS0701 - Discontinued
|
Cell line databases/resources |
cancercelllines; CVCL_4Y08
|
Encyclopedic resources |
Wikidata; Q54798466
|
Entry history |
Entry creation | 14-Dec-2015 |
Last entry update | 19-Dec-2024 |
Version number | 18 |
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