| Cell line name |
LoVo-Luc#2 |
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| Accession |
CVCL_4Y03 |
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| Resource Identification Initiative |
To cite this cell line use: LoVo-Luc#2 (RRID:CVCL_4Y03) |
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| Comments |
Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056. |
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| Sequence variations |
- Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1114Ter (c.3340C>T); ClinVar=VCV000236589; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Met1431fs*42 (c.4289delC) (p.T1430fs); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg2816Gln (c.8447G>A); ClinVar=VCV000419681; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Leu15Phefs*41 (c.43_44delCT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6768; SMAD2; Simple; p.Ala292Val (c.875C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0399 (LoVo) |
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| Sex of cell |
Male |
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| Age at sampling |
56Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): JCRB=JCRB1537
Markers:| Amelogenin | X,Y |
| CSF1PO | 11,13,14 |
| D5S818 | 11,13 |
| D7S820 | 9.3,10,11 |
| D13S317 | 8,11 |
| D16S539 | 9,12 |
| TH01 | 9.3 |
| TPOX | 8,9 |
| vWA | 17,18 |
Run an STR similarity search on this cell line |
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| Cross-references |
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| Cell line collections (Providers) |
JCRB; JCRB1537
JCRB; NIHS0717 - Discontinued
|
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| Cell line databases/resources |
cancercelllines; CVCL_4Y03
|
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| Encyclopedic resources |
Wikidata; Q54902902
|
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| Entry history |
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| Entry creation | 14-Dec-2015 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 18 |
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