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Cellosaurus LoVo-Luc#2 (CVCL_4Y03)

[Text version]
Cell line name LoVo-Luc#2
Accession CVCL_4Y03
Resource Identification Initiative To cite this cell line use: LoVo-Luc#2 (RRID:CVCL_4Y03)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Arg1114Ter (c.3340C>T); ClinVar=VCV000236589; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Met1431fs*42 (c.4289delC) (p.T1430fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Arg2816Gln (c.8447G>A); ClinVar=VCV000419681; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 914; B2M; Simple; p.Leu15Phefs*41 (c.43_44delCT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6768; SMAD2; Simple; p.Ala292Val (c.875C>T); Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0399 (LoVo)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1537

Markers:
AmelogeninX,Y
CSF1PO11,13,14
D5S81811,13
D7S8209.3,10,11
D13S3178,11
D16S5399,12
TH019.3
TPOX8,9
vWA17,18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1537
JCRB; NIHS0717 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4Y03
Encyclopedic resources Wikidata; Q54902902
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number17