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Cellosaurus NCI-H1975-Luc [JCRB] (CVCL_4W96)

[Text version]
Cell line name NCI-H1975-Luc [JCRB]
Accession CVCL_4W96
Resource Identification Initiative To cite this cell line use: NCI-H1975-Luc [JCRB] (RRID:CVCL_4W96)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Gly118Asp (c.353G>A); ClinVar=VCV000156446; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1511 (NCI-H1975)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1486

Markers:
AmelogeninX
CSF1PO12
D5S81811,12
D7S8208,11
D13S31710,13
D16S5399,12
TH017
TPOX8,11
vWA18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1486
JCRB; NIHS0724 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4W96
Encyclopedic resources Wikidata; Q54907893
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number16