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Cellosaurus HCC1937/CMV-Luc (CVCL_4W92)

[Text version]
Cell line name HCC1937/CMV-Luc
Synonyms HCC-1937/CMV-Luc
Accession CVCL_4W92
Resource Identification Initiative To cite this cell line use: HCC1937/CMV-Luc (RRID:CVCL_4W92)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Characteristics: Expression of luciferase is under the control of the CMV promoter.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Gln1756Profs*74 (c.5266dupC) (5382insC); ClinVar=VCV000017677; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Thr738_Arg775del38 (c.2212_2325del114); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Homozygous (from parent cell line).
Disease Breast ductal carcinoma (NCIt: C4017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0290 (HCC1937)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1508

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S8209,10
D13S31713
D16S53913,14
TH016
TPOX11
vWA16,17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1508
JCRB; NIHS0707 - Discontinued
Cell line databases/resources cancercelllines; CVCL_4W92
Encyclopedic resources Wikidata; Q54881614
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number20