ID   WRLS1
AC   CVCL_4W86
DR   Wikidata; Q54994416
RX   PubMed=23111106;
CC   Problematic cell line: Contaminated. Parent cell line (WRL-68) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_50924; Sorafenib (Nexavar).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0581 ! WRL 68
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 10-04-25; Version: 13
//
RX   PubMed=23111106; DOI=10.1016/j.canlet.2012.10.021;
RA   van Malenstein, Hannah
RA   Dekervel, Jeroen
RA   Verslype, Chris
RA   Van Cutsem, Eric
RA   Windmolders, Petra
RA   Nevens, Frederik
RA   van Pelt, Jos F.
RT   "Long-term exposure to sorafenib of liver cancer cells induces
RT   resistance with epithelial-to-mesenchymal transition, increased
RT   invasion and risk of rebound growth.";
RL   Cancer Lett. 329:74-83(2013).
//