ID   P388/NVB-2.5
AC   CVCL_4W04
SY   P388-N2.5; N2.5
DR   Wikidata; Q54937268
RX   PubMed=11488526;
RX   PubMed=18071633;
CC   Selected for resistance to: ChEBI; CHEBI:480999; Vinorelbine (Navelbine; NVB).
CC   Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Breed/subspecies: DBA/2.
DI   NCIt; C21602; Mouse lymphoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_D640 ! P388/S
SX   Female
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 21-03-23; Version: 6
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RX   PubMed=11488526; DOI=10.1007/s002800100275;
RA   Etievant C., Kruczynski A., Barret J.-M., Tait A.S., Kavallaris M.,
RA   Hill B.T.;
RT   "Markedly diminished drug resistance-inducing properties of vinflunine
RT   (20',20'-difluoro-3',4'-dihydrovinorelbine) relative to vinorelbine,
RT   identified in murine and human tumour cells in vivo and in vitro.";
RL   Cancer Chemother. Pharmacol. 48:62-70(2001).
//
RX   PubMed=18071633; DOI=10.1007/s10637-007-9102-3;
RA   Aggarwal A., Kruczynski A., Frankfurter A., Correia J.J., Lobert S.;
RT   "Murine leukemia P388 vinorelbine-resistant cell lines are sensitive
RT   to vinflunine.";
RL   Invest. New Drugs 26:319-330(2008).
//