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Cellosaurus V79NHh1A2 (CVCL_4V40)

[Text version]
Cell line name V79NHh1A2
Synonyms XEMhIA2-NH#1; XEMhIA2NH
Accession CVCL_4V40
Resource Identification Initiative To cite this cell line use: V79NHh1A2 (RRID:CVCL_4V40)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2596; CYP1A2.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V38 (V79NH)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=1446722; DOI=10.1016/0926-6917(92)90017-7
Wolfel C., Heinrich-Hirsch B., Schulz-Schalge T., Seidel A., Frank H., Ramp U., Wachter F., Wiebel F.J., Gonzalez F.J., Greim H., Doehmer J.
Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2.
Eur. J. Pharmacol. 228:95-102(1992)

PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Schmalix W.A., Maser H., Kiefer F., Reen R., Wiebel F.J., Gonzalez F.J., Seidel A., Glatt H.-R., Greim H., Doehmer J.
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993)

Cross-references
Encyclopedic resources Wikidata; Q54992637
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number10