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Cellosaurus V79-hCYP1A1 (CVCL_4V37)

[Text version]
Cell line name V79-hCYP1A1
Synonyms V79MZ-h1A1; V79MZh1A1
Accession CVCL_4V37
Resource Identification Initiative To cite this cell line use: V79-hCYP1A1 (RRID:CVCL_4V37)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2595; CYP1A1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V36 (V79MZ)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Schmalix W.A., Maser H., Kiefer F., Reen R., Wiebel F.J., Gonzalez F.J., Seidel A., Glatt H.-R., Greim H., Doehmer J.
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993)

PubMed=9625737; DOI=10.1021/tx970236p
Luch A., Coffing S.L., Tang Y.M., Schneider A., Soballa V., Greim H., Jefcoate C.R., Seidel A., Greenlee W.F., Baird W.M., Doehmer J.
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.
Chem. Res. Toxicol. 11:686-695(1998)

Cross-references
Encyclopedic resources Wikidata; Q54992631
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number10