ID   HROG17
AC   CVCL_4U45
DR   cancercelllines; CVCL_4U45
DR   CLS; 300938
DR   PRIDE; PXD020079
DR   Wikidata; Q54895317
RX   PubMed=23951083;
RX   PubMed=33592498;
CC   From: Linnebacher, Michael; University of Rostock; Rostock; Germany.
CC   Population: Caucasian.
CC   Doubling time: 32-42 hours (CLS=300938).
CC   HLA typing: A*11:01,66:01; B*14:02,40:02; C*01:02,08:02; DPA1*01:03,02:01; DPB1*04:01,11:01; DQA1*01:01,05:05; DQB1*03:01,05:01; DRB1*01:02,12:01; DRB3*02:02 (PubMed=33592498).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Unspecified (CLS=300938).
CC   Omics: Deep exome analysis.
CC   Omics: HLA class I peptidome analysis by proteomics.
CC   Omics: HLA class II peptidome analysis by proteomics.
CC   Derived from site: In situ; Brain, left parieto-occipital lobe.
ST   Source(s): CLS=300938
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D12S391: 17,19.3
ST   D13S317: 9,11
ST   D16S539: 10,11
ST   D18S51: 16,17
ST   D19S433: 12,15
ST   D1S1656: 15,16
ST   D21S11: 29,30
ST   D2S1338: 17,19
ST   D3S1358: 16,17
ST   D5S818: 11,12
ST   D6S1043: 12,17
ST   D7S820: 9,10
ST   D8S1179: 12,15
ST   FGA: 25
ST   Penta D: 9,15
ST   Penta E: 7,20
ST   TH01: 9,9.3
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B7FQ ! HROG17 T1 M1
SX   Male
AG   70Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 19-12-24; Version: 16
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RX   PubMed=23951083; DOI=10.1371/journal.pone.0071070; PMCID=PMC3737284;
RA   Mullins C.S., Schneider B., Stockhammer F., Krohn M., Classen C.F.,
RA   Linnebacher M.;
RT   "Establishment and characterization of primary glioblastoma cell lines
RT   from fresh and frozen material: a detailed comparison.";
RL   PLoS ONE 8:E71070-E71070(2013).
//
RX   PubMed=33592498; DOI=10.1074/mcp.RA120.002201; PMCID=PMC8724627;
RA   Forlani G., Michaux J., Pak H., Huber F., Lauret Marie-Joseph E.,
RA   Ramia E., Stevenson B.J., Linnebacher M., Accolla R.S.,
RA   Bassani-Sternberg M.;
RT   "CIITA-transduced glioblastoma cells uncover a rich repertoire of
RT   clinically relevant tumor-associated HLA-II antigens.";
RL   Mol. Cell. Proteomics 20:100032.1-100032.21(2021).
//