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Cellosaurus AC10 (CVCL_4U16)

[Text version]
Cell line name AC10
Accession CVCL_4U16
Resource Identification Initiative To cite this cell line use: AC10 (RRID:CVCL_4U16)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-1501.
Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
Derived from site: In situ; Heart, ventricle; UBERON=UBERON_0002082.
Cell type: Cardiomyocyte; CL=CL_0002495.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4U14 (DWFb1-rho0)
Category Hybrid cell line
Publications

PubMed=15913645; DOI=10.1016/j.yjmcc.2005.03.003
Davidson M.M., Nesti C., Palenzuela L., Walker W.F., Hernandez E., Protas L., Hirano M., Isaac N.D.
Novel cell lines derived from adult human ventricular cardiomyocytes.
J. Mol. Cell. Cardiol. 39:133-147(2005)

Patent=US7223599
Davidson M.M.
Immortalization of human post-mitotic cells.
Patent number US7223599, 29-May-2007

Cross-references
Cell line collections (Providers) ATCC; CRL-3569
Encyclopedic resources Wikidata; Q54607914
Entry history
Entry creation22-Sep-2015
Last entry update10-Sep-2024
Version number8