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Cellosaurus AC1 [Human hybrid cardiomyocyte] (CVCL_4U15)

[Text version]
Cell line name AC1 [Human hybrid cardiomyocyte]
Accession CVCL_4U15
Resource Identification Initiative To cite this cell line use: AC1 [Human hybrid cardiomyocyte] (RRID:CVCL_4U15)
Comments Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
Derived from site: In situ; Heart, ventricle; UBERON=UBERON_0002082.
Cell type: Cardiomyocyte; CL=CL_0002495.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4U14 (DWFb1-rho0)
Category Hybrid cell line
Publications

PubMed=15913645; DOI=10.1016/j.yjmcc.2005.03.003
Davidson M.M., Nesti C., Palenzuela L., Walker W.F., Hernandez E., Protas L., Hirano M., Isaac N.D.
Novel cell lines derived from adult human ventricular cardiomyocytes.
J. Mol. Cell. Cardiol. 39:133-147(2005)

Cross-references
Encyclopedic resources Wikidata; Q54607901
Entry history
Entry creation22-Sep-2015
Last entry update10-Sep-2024
Version number6