Cellosaurus cell line SV-BR-1-GM (CVCL

Cellosaurus SV-BR-1-GM (CVCL_4U13)

Cross-references
Cell line name	SV-BR-1-GM
Synonyms	SVBR-1-GM
Accession	CVCL_4U13
Resource Identification Initiative	To cite this cell line use: SV-BR-1-GM (RRID:CVCL_4U13)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-7813. Characteristics: ER/PR-negative and ERBB2-positive. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2434; CSF2. Derived from site: Metastatic; Chest wall; UBERON=UBERON_0016435.
Disease	Breast carcinoma (NCIt: C4872)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4U12 (SV-BR-1)
Sex of cell	Female
Age at sampling	39Y
Category	Cancer cell line
Publications	PubMed=16958969; DOI=10.1111/j.1075-122X.2006.00319.x Wiseman C.L., Kharazi A. Objective clinical regression of metastatic breast cancer in disparate sites after use of whole-cell vaccine genetically modified to release sargramostim. Breast J. 12:475-480(2006) Patent=US7674456 Wiseman C.L., Kharazi A. Breast cancer cell lines and uses thereof. Patent number US7674456, 09-Mar-2010 PubMed=29867922; DOI=10.3389/fimmu.2018.00776; PMCID=PMC5962696 Lacher M.D., Bauer G., Fury B., Graeve S., Fledderman E.L., Petrie T.D., Coleal-Bergum D.P., Hackett T., Perotti N.H., Kong Y.Y., Kwok W.W., Wagner J.P., Wiseman C.L., Williams W.V. SV-BR-1-GM, a clinically effective GM-CSF-secreting breast cancer cell line, expresses an immune signature and directly activates CD4(+) T lymphocytes. Front. Immunol. 9:776.1-776.23(2018)
Encyclopedic resources	Wikidata; Q54970930
Entry history
Entry creation	22-Sep-2015
Last entry update	19-Dec-2024
Version number	9