Cell line name |
KM12-HX |
Synonyms |
KM12HX |
Accession |
CVCL_4M93 |
Resource Identification Initiative |
To cite this cell line use: KM12-HX (RRID:CVCL_4M93) |
Comments |
Population: Caucasian. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Gene fusion; HGNC; 8031; NTRK1 + HGNC; 12012; TPM3; Name(s)=TPM3-NTRK1 (from parent cell line).
- Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 583; APC; Simple; p.Asn1819fs*7 (c.5454_5455insA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 1101; BRCA2; Simple; p.Asn1784Hisfs*7 (c.5350_5351delAA); ClinVar=VCV000037959; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Gly129Ter (c.385G>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Lys267Argfs*9 (c.800delA) (p.Leu265fs, c.795delA); ClinVar=VCV000092828; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Val73Trpfs*50 (c.216delC) (p.P72fs); ClinVar=VCV000428897; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.His179Arg (c.536A>G); ClinVar=VCV000376606; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Colon carcinoma (NCIt: C4910) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_9547 (KM12-C) |
Sex of cell |
Male |
Age at sampling |
Age unspecified |
Category |
Cancer cell line |
Publications | PubMed=1679016; DOI=10.1016/0014-4827(91)90451-Y Matsushita Y., Nakamori S., Seftor E.A., Hendrix M.J.C., Irimura T. Human colon carcinoma cells with increased invasive capacity obtained by selection for sialyl-dimeric LeX antigen. Exp. Cell Res. 196:20-25(1991) PubMed=7529188; DOI=10.1006/excr.1995.1027 Izumi Y., Taniuchi Y., Tsuji T., Smith C.W., Nakamori S., Fidler I.J., Irimura T. Characterization of human colon carcinoma variant cells selected for sialyl Lex carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells. Exp. Cell Res. 216:215-221(1995) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_4M93
|
Encyclopedic resources |
Wikidata; Q54900055
|
Entry history |
Entry creation | 22-Sep-2015 |
Last entry update | 05-Oct-2023 |
Version number | 11 |
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