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Cellosaurus AG08243 (CVCL_4K36)

[Text version]
Cell line name AG08243
Accession CVCL_4K36
Resource Identification Initiative To cite this cell line use: AG08243 (RRID:CVCL_4K36)
Comments Population: Caucasian.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 613; APOE; Simple; p.Arg130Cys (c.388C>T); Zygosity=Homozygous; Note=ApoE3 allele (PubMed=30699343).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A9ZR (AG27605)
Originate from same individual CVCL_4K35 ! AG08242
Sex of cell Male
Age at sampling 72Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=7847674; DOI=10.1111/j.1749-6632.1994.tb44413.x
Etcheberrigaray R., Gibson G.E., Alkon D.L.
Molecular mechanisms of memory and the pathophysiology of Alzheimer's disease.
Ann. N. Y. Acad. Sci. 747:245-255(1994)

PubMed=10408806; DOI=10.1006/nbdi.1999.0236
Geller L.N., Potter H.
Chromosome missegregation and trisomy 21 mosaicism in Alzheimer's disease.
Neurobiol. Dis. 6:167-179(1999)

PubMed=30699343; DOI=10.1016/j.celrep.2019.01.023; PMCID=PMC6386196
Meyer K., Feldman H.M., Lu T., Drake D., Lim E.T., Ling K.-H., Bishop N.A., Pan Y., Seo J., Lin Y.-T., Su S.C., Church G.M., Tsai L.-H., Yankner B.A.
REST and neural gene network dysregulation in iPSC models of Alzheimer's disease.
Cell Rep. 26:1112-1127.e9(2019)

Cross-references
Cell line collections (Providers) Coriell; AG08243
Cell line databases/resources CLO; CLO_0034032
Encyclopedic resources Wikidata; Q54741767
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number11