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Cellosaurus SKG-II/TS (CVCL_4J77)

[Text version]
Cell line name SKG-II/TS
Synonyms SKG-II-TS
Accession CVCL_4J77
Resource Identification Initiative To cite this cell line use: SKG-II/TS (RRID:CVCL_4J77)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 12441; TYMS.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Sequence variations
  • Mutation; HGNC; 7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Unspecified (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2794 (SKG-II)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=12239455; DOI=10.1159/000063804
Saga Y., Suzuki M., Mizukami H., Urabe M., Fukushima M., Ozawa K., Sato I.
Enhanced expression of thymidylate synthase mediates resistance of uterine cervical cancer cells to radiation.
Oncology 63:185-191(2002)

PubMed=12845668; DOI=10.1002/ijc.11221
Saga Y., Suzuki M., Mizukami H., Kohno T., Takei Y., Fukushima M., Ozawa K.
Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
Int. J. Cancer 106:324-326(2003)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01914
Encyclopedic resources Wikidata; Q54954731
Entry history
Entry creation22-Sep-2015
Last entry update10-Sep-2024
Version number12