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Cellosaurus MM28 (CVCL_4D15)

[Text version]
Cell line name MM28
Accession CVCL_4D15
Resource Identification Initiative To cite this cell line use: MM28 (RRID:CVCL_4D15)
Comments Doubling time: 109 hours (PubMed=24994677).
Omics: SNP array analysis.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:950; BAP1; Simple; p.Tyr627Ter (c.1881C>A); Zygosity=Unspecified (PubMed=24994677).
  • Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Unspecified (PubMed=24994677).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3295; PubMed=24994677

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811
D7S8208,10
D13S3178,11
D16S53910,12
D21S1128,29
TH017,9.3
TPOX11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=24994677; DOI=10.1016/j.molonc.2014.06.004; PMCID=PMC5528590
Amirouchene-Angelozzi N., Nemati F., Gentien D., Nicolas A., Dumont A., Carita G., Camonis J., Desjardins L., Cassoux N., Piperno-Neumann S., Mariani P., Sastre-Garau X., Decaudin D., Roman-Roman S.
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Mol. Oncol. 8:1508-1520(2014)

Cross-references
Cell line collections (Providers) ATCC; CRL-3295
Cell line databases/resources cancercelllines; CVCL_4D15
Encyclopedic resources Wikidata; Q54906090
Polymorphism and mutation databases IARC_TP53; 23398
Entry history
Entry creation22-Sep-2015
Last entry update19-Dec-2024
Version number13