ID   HX/62
AC   CVCL_4995
SY   HX-62; HX 62; HX62; Hx62
DR   cancercelllines; CVCL_4995
DR   ChEMBL-Cells; CHEMBL3308618
DR   ChEMBL-Targets; CHEMBL614686
DR   Cosmic; 1609539
DR   GEO; GSM313712
DR   Progenetix; CVCL_4995
DR   PubChem_Cell_line; CVCL_4995
DR   Wikidata; Q54896958
RX   PubMed=1423261;
RX   PubMed=1892748;
RX   PubMed=2653399;
RX   PubMed=15677628;
CC   Population: Caucasian.
CC   Characteristics: Established from a xenograft established in female nude mice (PubMed=2653399).
CC   Doubling time: 32 hours (PubMed=2653399).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 18
//
RX   PubMed=1423261;
RA   Mistry P., Kelland L.R., Loh S.Y., Abel G., Murrer B.A., Harrap K.R.;
RT   "Comparison of cellular accumulation and cytotoxicity of cisplatin
RT   with that of tetraplatin and
RT   amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human
RT   ovarian carcinoma cell lines.";
RL   Cancer Res. 52:6188-6193(1992).
//
RX   PubMed=1892748; DOI=10.1038/bjc.1991.279;
RA   Mistry P., Kelland L.R., Abel G., Sidhar S., Harrap K.R.;
RT   "The relationships between glutathione, glutathione-S-transferase and
RT   cytotoxicity of platinum drugs and melphalan in eight human ovarian
RT   carcinoma cell lines.";
RL   Br. J. Cancer 64:215-220(1991).
//
RX   PubMed=2653399; DOI=10.1038/bjc.1989.108;
RA   Hills C.A., Kelland L.R., Abel G., Siracky J., Wilson A.P.,
RA   Harrap K.R.;
RT   "Biological properties of ten human ovarian carcinoma cell lines:
RT   calibration in vitro against four platinum complexes.";
RL   Br. J. Cancer 59:527-534(1989).
//
RX   PubMed=15677628; DOI=10.1093/carcin/bgi032;
RA   Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C.,
RA   Edwards P.A.W., Caldas C.;
RT   "Evidence that both genetic instability and selection contribute to
RT   the accumulation of chromosome alterations in cancer.";
RL   Carcinogenesis 26:923-930(2005).
//