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Cellosaurus PC-93 (CVCL_4888)

[Text version]
Cell line name PC-93
Accession CVCL_4888
Resource Identification Initiative To cite this cell line use: PC-93 (RRID:CVCL_4888)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=14518029; PubMed=20143388). Originally thought to originate from a moderately differentiated primary adenocarcinoma of the prostate.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00256.
Population: African American.
Doubling time: 20 hours (PubMed=6602397).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=6602397; DOI=10.1111/j.1399-0039.1983.tb00162.x
Claas F.H.J., van Steenbrugge G.J.
Expression of HLA-like structures on a permanent human tumor line PC-93.
Tissue Antigens 21:227-232(1983)

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Russell P.J., Kingsley E.A.
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=14518029; DOI=10.1002/pros.10290
van Bokhoven A., Varella-Garcia M., Korch C.T., Johannes W.U., Smith E.E., Miller H.L., Nordeen S.K., Miller G.J., Lucia M.S.
Molecular characterization of human prostate carcinoma cell lines.
Prostate 57:205-225(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151752
Encyclopedic resources Wikidata; Q54086637
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number22