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Cellosaurus ACH-3P (CVCL_4829)

[Text version]
Cell line name ACH-3P
Synonyms ACH 3P
Accession CVCL_4829
Resource Identification Initiative To cite this cell line use: ACH-3P (RRID:CVCL_4829)
Comments Characteristics: Fusion of the AC1-1 choriocarcinoma cell line with primary first trimester trophoblasts (week 12 of gestation) (PubMed=18093301).
Karyotypic information: Near tetraploid karyotype (PubMed=33096371).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9560 (AC1-1)
Category Hybrid cell line
STR profile Source(s): PubMed=33810901

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D1S165614,16
D2S44110,12,14
D2S133820,22,24
D3S135815,16,18
D5S81810,11
D7S82010,12,13
D8S117912
D10S124813,14,15
D12S39117,19,21,24
D13S3179,11
D16S53912,13,14
D18S5113,14,15
D19S43313,15
D21S1130,31
D22S104515,16
FGA21,22,23
Penta D8,9,12,14
Penta E5,8,12
SE3315,36
TH019,9.3
TPOX8,11,12
vWA14,16

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Publications

PubMed=18093301; DOI=10.1186/1471-213X-7-137; PMCID=PMC2263055
Hiden U., Wadsack C., Prutsch N., Gauster M., Weiss U., Frank H.-G., Schmitz U., Fast-Hirsch C., Hengstschlager M., Potgens A., Ruben A., Knofler M., Haslinger P., Huppertz B., Bilban M., Kaufmann P., Desoye G.
The first trimester human trophoblast cell line ACH-3P: a novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations -- TNF-alpha stimulates MMP15 expression.
BMC Dev. Biol. 7:137.1-137.13(2007)

PubMed=28724925; DOI=10.1038/s41598-017-06364-z; PMCID=PMC5517571
Rothbauer M., Patel N., Gondola H., Siwetz M., Huppertz B., Ertl P.
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892-5892(2017)

PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Weber M., Weise A., Vasheghani F., Gohner C., Fitzgerald J.S., Liehr T., Markert U.R.
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)

PubMed=33810901; DOI=10.1016/j.placenta.2021.02.022
Pastuschek J., Nonn O., Gutierrez-Samudio R.N., Murrieta-Coxca J.M., Muller J., Sanft J., Huppertz B., Markert U.R., Groten T., Morales-Prieto D.M.
Molecular characteristics of established trophoblast-derived cell lines.
Placenta 108:122-133(2021)

Cross-references
Anatomy/cell type resources BTO; BTO:0003421
Encyclopedic resources Wikidata; Q54608363
Experimental variables resources EFO; EFO_0006269
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number10