ID   1542-CPTX-1
AC   CVCL_4821
SY   1542-CP1TX; 1542T
DR   Wikidata; Q54582092
RX   PubMed=9041206;
RX   PubMed=10913677;
RX   PubMed=16235240;
WW   https://web.archive.org/web/20160703200804/http://capcelllines.ca:80/details.asp?id=99
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_4822 ! 1542-CPTX-2
OI   CVCL_4823 ! 1542-CPTX-3
OI   CVCL_4824 ! 1542-normal
OI   CVCL_4825 ! 1542-seminal vesicle
SX   Male
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 14
//
RX   PubMed=9041206;
RA   Bright R.K., Vocke C.D., Emmert-Buck M.R., Duray P.H., Solomon D.,
RA   Fetsch P.A., Rhim J.S., Linehan W.M., Topalian S.L.;
RT   "Generation and genetic characterization of immortal human prostate
RT   epithelial cell lines derived from primary cancer specimens.";
RL   Cancer Res. 57:995-1002(1997).
//
RX   PubMed=10913677; DOI=10.1016/S0165-4608(99)00248-4;
RA   Macoska J.A., Beheshti B., Rhim J.S., Hukku B., Lehr J., Pienta K.J.,
RA   Squire J.A.;
RT   "Genetic characterization of immortalized human prostate epithelial
RT   cell cultures. Evidence for structural rearrangements of chromosome 8
RT   and i(8q) chromosome formation in primary tumor-derived cells.";
RL   Cancer Genet. Cytogenet. 120:50-57(2000).
//
RX   PubMed=16235240; DOI=10.1002/gcc.20274;
RA   Begley L., Keeney D., Beheshti B., Squire J.A., Kant R., Chaib H.,
RA   MacDonald J.W., Rhim J.S., Macoska J.A.;
RT   "Concordant copy number and transcriptional activity of genes mapping
RT   to derivative chromosomes 8 during cellular immortalization in
RT   vitro.";
RL   Genes Chromosomes Cancer 45:136-146(2006).
//