ID   Z-33
AC   CVCL_4796
SY   Z33
DR   ATCC; CRL-3393
DR   Wikidata; Q54995851
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=8751477;
RX   PubMed=10071072;
RX   PubMed=10576511;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=Z-33
CC   Population: Caucasian.
CC   Doubling time: 24-30 hours (PubMed=8751477).
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 1 fused to ABL1 exon 2 (e1a2 transcript) (PubMed=8751477; PubMed=10071072; PubMed=10576511).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C114819; Adult B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_585909; B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 21
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=8751477;
RA   Estrov Z., Talpaz M., Ku S., Harris D., LaPushin R., Koller C.A.,
RA   Hirsch-Ginsberg C.F., Huh Y.O., Yee G., Kurzrock R.;
RT   "Molecular and biologic characterization of a newly established
RT   Philadelphia-positive acute lymphoblastic leukemia cell line (Z-33)
RT   with an autocrine response to GM-CSF.";
RL   Leukemia 10:1534-1543(1996).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//