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Cellosaurus A-875 (CVCL_4733)

[Text version]
Cell line name A-875
Synonyms A875; 875
Accession CVCL_4733
Resource Identification Initiative To cite this cell line use: A-875 (RRID:CVCL_4733)
Comments Doubling time: ~4 days (PubMed=265522).
Omics: Transcriptome analysis by RNAseq.
Caution: Incorrectly indicated in table 2 of PubMed=265522 to originate from a 78 year old male.
Derived from site: Metastatic; Brain, right frontal lobe; UBERON=UBERON_0002810.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): CCRID; CLS=305099

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,24
D3S135814,15
D5S81811,13
D7S8208,11
D8S117911
D13S3178,12
D16S53911,12
D18S5117
D19S43313.2,14
D21S1128,30.2
FGA22
Penta D10,12
Penta E7
TH019.3
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-568.html
Publications

PubMed=4357758; DOI=10.1093/jnci/51.5.1417
Giard D.J., Aaronson S.A., Todaro G.J., Arnstein P., Kersey J.H., Dosik H., Parks W.P.
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.
J. Natl. Cancer Inst. 51:1417-1423(1973)

PubMed=265522; DOI=10.1073/pnas.74.2.565; PMCID=PMC392331
Fabricant R.N., De Larco J.E., Todaro G.J.
Nerve growth factor receptors on human melanoma cells in culture.
Proc. Natl. Acad. Sci. U.S.A. 74:565-569(1977)

PubMed=375235; DOI=10.1073/pnas.76.3.1288; PMCID=PMC383236
Sherwin S.A., Sliski A.H., Todaro G.J.
Human melanoma cells have both nerve growth factor and nerve growth factor-specific receptors on their cell surfaces.
Proc. Natl. Acad. Sci. U.S.A. 76:1288-1292(1979)

PubMed=6256643; DOI=10.1038/288724a0
Day R.S. 3rd, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A., Lubiniecki A.S., Girardi A.J., Galloway S.M., Bynum G.D.
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains.
Nature 288:724-727(1980)

PubMed=6988327; DOI=10.1007/BF02831503
O'Brien S.J., Shannon J.E., Gail M.H.
A molecular approach to the identification and individualization of human and animal cells in culture: isozyme and allozyme genetic signatures.
In Vitro 16:119-135(1980)

PubMed=25502142; DOI=10.1038/ncomms6712; PMCID=PMC4428333
Muller J., Krijgsman O., Tsoi J., Robert L., Hugo W., Song C., Kong X.-J., Possik P.A., Cornelissen-Steijger P.D.M., Geukes Foppen M.H., Kemper K., Goding C.R., McDermott U., Blank C., Haanen J.B.A.G., Graeber T.G., Ribas A., Lo R.S., Peeper D.S.
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Nat. Commun. 5:5712.1-5712.15(2014)

Cross-references
Cell line collections (Providers) CCTCC; GDC0312
CLS; 305099
KCB; KCB 2012028YJ
Cell line databases/resources CCRID; 1101HUM-PUMC000094
CCRID; 4201HUM-CCTCC00312
Anatomy/cell type resources BTO; BTO_0000525
Encyclopedic resources Wikidata; Q54606065
Gene expression databases GEO; GSM1507933
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21