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Cellosaurus V79MZh11B2 (CVCL_4710)

[Text version]
Cell line name V79MZh11B2
Accession CVCL_4710
Resource Identification Initiative To cite this cell line use: V79MZh11B2 (RRID:CVCL_4710)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2592; CYP11B2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V36 (V79MZ)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=7588408; DOI=10.3109/07435809509030460
Denner K., Doehmer J., Bernhardt R.
Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their functional expression in COS-7 and V79 Chinese hamster cells.
Endocr. Res. 21:443-448(1995)

PubMed=12530636; DOI=10.1081/ERC-120016808
Bureik M., Zeeh A., Bernhardt R.
Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.
Endocr. Res. 28:351-355(2002)

Cross-references
Anatomy/cell type resources BTO; BTO:0003279
Encyclopedic resources Wikidata; Q54992628
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number14