ID   V79MZh11B1
AC   CVCL_4709
DR   BTO; BTO:0003278
DR   Wikidata; Q54992626
RX   PubMed=7588408;
RX   PubMed=12530636;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 2591; CYP11B1.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 14
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RX   PubMed=7588408; DOI=10.3109/07435809509030460;
RA   Denner K., Doehmer J., Bernhardt R.;
RT   "Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their
RT   functional expression in COS-7 and V79 Chinese hamster cells.";
RL   Endocr. Res. 21:443-448(1995).
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RX   PubMed=12530636; DOI=10.1081/ERC-120016808;
RA   Bureik M., Zeeh A., Bernhardt R.;
RT   "Modulation of steroid hydroxylase activity in stably transfected
RT   V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.";
RL   Endocr. Res. 28:351-355(2002).
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