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Cellosaurus DC3F/ADX (CVCL_4705)

[Text version]
Cell line name DC3F/ADX
Synonyms DC3F/Adx; DC3F-ADX; DC-3F/ADX; DC-3F/AD X
Accession CVCL_4705
Resource Identification Initiative To cite this cell line use: DC3F/ADX (RRID:CVCL_4705)
Comments Selected for resistance to: ChEBI; CHEBI_27666; Actinomycin D (ActD).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_GZ08 (DC3F/ADIV)
Children:
CVCL_5A42 (DC3F/ADXC)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=5533992
Biedler J.L., Riehm H.
Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.
Cancer Res. 30:1174-1184(1970)

PubMed=3365701
Biedler J.L., Chang T.-D., Scotto K.W., Melera P.W., Spengler B.A.
Chromosomal organization of amplified genes in multidrug-resistant Chinese hamster cells.
Cancer Res. 48:3179-3187(1988)

PubMed=2158805; DOI=10.1038/bjc.1990.127; PMCID=PMC1971365
Boscoboinik D.O., Gupta R.S., Epand R.M.
Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells.
Br. J. Cancer 61:568-572(1990)

PubMed=7907088; DOI=10.1016/S0021-9258(17)37579-8
Devine S.E., Melera P.W.
Diversity of multidrug resistance in mammalian cells.
J. Biol. Chem. 269:6133-6139(1994)

PubMed=11455011; DOI=10.1124/mol.60.2.254
Song J., Melera P.W.
Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein that affects drug resistance and cooperates with TM6 to mediate [125I]iodoarylazidoprazosin labeling.
Mol. Pharmacol. 60:254-261(2001)

Cross-references
Anatomy/cell type resources BTO; BTO_0002395
Encyclopedic resources Wikidata; Q54828628
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number12