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Cellosaurus CHO-6 (CVCL_4700)

[Text version]
Cell line name CHO-6
Synonyms CHO6; CHO 6
Accession CVCL_4700
Resource Identification Initiative To cite this cell line use: CHO-6 (RRID:CVCL_4700)
Comments Characteristics: Resistant to infection by Chlamydia pneumoniae, Chlamydia psittaci and Chlamydia trachomatis.
Characteristics: Has a defect in the processing of the signal sequence of P4HB/PDIA1 which lead to impaired chlamydial attachment and infectivity.
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=12379725; DOI=10.1128/IAI.70.11.6444-6447.2002; PMCID=PMC130417
Fudyk T., Olinger L., Stephens R.S.
Selection of mutant cell lines resistant to infection by Chlamydia spp.
Infect. Immun. 70:6444-6447(2002)

PubMed=16925789; DOI=10.1111/j.1462-5822.2006.00783.x
Conant C.G., Stephens R.S.
Chlamydia attachment to mammalian cells requires protein disulfide isomerase.
Cell. Microbiol. 9:222-232(2007)

Cross-references
Anatomy/cell type resources BTO; BTO:0003450
Encyclopedic resources Wikidata; Q54812618
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number10