ID   RLE-6TN
AC   CVCL_4693
SY   Rat Lung Epithelial-6-T-antigen Negative
DR   BTO; BTO_0003510
DR   CLO; CLO_0008835
DR   AddexBio; C0016014/4948
DR   ATCC; CRL-2300
DR   IZSLER; BS CL 206
DR   Wikidata; Q54950601
RX   PubMed=8528500;
RX   PubMed=12740220;
CC   Characteristics: While transfected with SV40 pRSV-T, does not express SV40 T antigen thus said to be derived from a spontaneous transformant.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: Fischer 344; RS=RS:0000215.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
OI   CVCL_LB71 ! RLE-6T
SX   Male
AG   56D
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
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RX   PubMed=8528500; DOI=10.1007/BF02634029;
RA   Driscoll K.E., Carter J.M., Iype P.T., Kumari H.L., Crosby L.L.,
RA   Aardema M.J., Isfort R.J., Cody D., Chestnut M.H., Burns J.L.,
RA   LeBoeuf R.A.;
RT   "Establishment of immortalized alveolar type II epithelial cell lines
RT   from adult rats.";
RL   In Vitro Cell. Dev. Biol. Anim. 31:516-527(1995).
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RX   PubMed=12740220; DOI=10.1152/ajplung.00376.2002;
RA   Lei J.-X., Nowbar S., Mariash C.N., Ingbar D.H.;
RT   "Thyroid hormone stimulates Na-K-ATPase activity and its plasma
RT   membrane insertion in rat alveolar epithelial cells.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 285:L762-L772(2003).
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