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Cellosaurus HL-60-R2 (CVCL_4635)

[Text version]
Cell line name HL-60-R2
Accession CVCL_4635
Resource Identification Initiative To cite this cell line use: HL-60-R2 (RRID:CVCL_4635)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27300; Vitamin D.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO13,14
D5S81812
D7S82011,12
D13S3178,11
D16S53911
TH017,8
TPOX8,11
vWA16

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Cross-references
Cell line collections (Providers) RCB; RCB1550
Cell line databases/resources CLO; CLO_0051006
cancercelllines; CVCL_4635
Encyclopedic resources Wikidata; Q54889811
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number24