ID   LIM2550
AC   CVCL_4442
SY   LIM 2550; LIM-2550
DR   BioSample; SAMN07624417
DR   cancercelllines; CVCL_4442
DR   CBA; CBA-0169
DR   ColonAtlas; LIM2550
DR   Cosmic; 1238058
DR   Cosmic; 1486140
DR   Cosmic; 1805262
DR   ECACC; 12070504
DR   GEO; GSM1448168
DR   Wikidata; Q54902540
RX   PubMed=19378335;
RX   PubMed=25926053;
CC   From: Ludwig Institute for Cancer Research, Melbourne Branch; Melbourne; Australia.
CC   Microsatellite instability: Instable (MSI) (PubMed=19378335; PubMed=25926053).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Heterozygous (PubMed=19378335).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (PubMed=19378335).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Asp (c.734G>A); ClinVar=VCV000012355; Zygosity=Unspecified (PubMed=19378335).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
ST   Source(s): CBA=CBA-0169; PubMed=25926053
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12,15
ST   D16S539: 9,14
ST   D18S51: 13,14
ST   D19S433: 11,14
ST   D21S11: 29,31.2
ST   D2S1338: 17,23
ST   D3S1358: 15,18
ST   D5S818: 12,13
ST   D7S820: 9,10
ST   D8S1179: 14,15
ST   FGA: 21,22
ST   TH01: 8,9
ST   TPOX: 8
ST   vWA: 14,19
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 27
//
RX   PubMed=19378335; DOI=10.1002/ijc.24289;
RA   Zhang H.-H., Walker F.E., Kiflemariam S., Whitehead R.H., Williams D.,
RA   Phillips W.A., Mikeska T., Dobrovic A., Burgess A.W.;
RT   "Selective inhibition of proliferation in colorectal carcinoma cell
RT   lines expressing mutant APC or activated B-Raf.";
RL   Int. J. Cancer 125:297-307(2009).
//
RX   PubMed=25926053; DOI=10.1038/ncomms8002;
RA   Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G.,
RA   Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S.,
RA   Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M.,
RA   Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.;
RT   "The molecular landscape of colorectal cancer cell lines unveils
RT   clinically actionable kinase targets.";
RL   Nat. Commun. 6:7002.1-7002.10(2015).
//