ID   AE17
AC   CVCL_4408
DR   CBA; CBA-0156
DR   ECACC; 10092310
DR   Wikidata; Q54608901
RX   PubMed=14607902;
RX   PubMed=22581112;
RX   PubMed=28577549;
CC   Sequence variation: Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (PubMed=28577549).
CC   Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos.
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Breed/subspecies: C57BL/6J.
DI   NCIt; C21619; Mouse mesothelioma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=14607902; DOI=10.4049/jimmunol.171.10.5051;
RA   Jackaman C., Bundell C.S., Kinnear B.F., Smith A.M., Filion P.,
RA   van Hagen D., Robinson B.W.S., Nelson D.J.;
RT   "IL-2 intratumoral immunotherapy enhances CD8+ T cells that mediate
RT   destruction of tumor cells and tumor-associated vasculature: a novel
RT   mechanism for IL-2.";
RL   J. Immunol. 171:5051-5063(2003).
//
RX   PubMed=22581112; DOI=10.3892/or.2012.1809;
RA   Fox S.A., Loh S.S., Mahendran S.K., Garlepp M.J.;
RT   "Regulated chemokine gene expression in mouse mesothelioma and
RT   mesothelial cells: TNF-alpha upregulates both CC and CXC chemokine
RT   genes.";
RL   Oncol. Rep. 28:707-713(2012).
//
RX   PubMed=28577549; DOI=10.1186/s12885-017-3382-6; PMCID=PMC5455120;
RA   Sneddon S., Patch A.-M., Dick I.M., Kazakoff S.H., Pearson J.V.,
RA   Waddell N., Allcock R.J.N., Holt R.A., Robinson B.W.S., Creaney J.;
RT   "Whole exome sequencing of an asbestos-induced wild-type murine model
RT   of malignant mesothelioma.";
RL   BMC Cancer 17:396.1-396.10(2017).
//