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Cellosaurus SK-PC-3 (CVCL_4055)

[Text version]
Cell line name SK-PC-3
Synonyms PC3
Accession CVCL_4055
Resource Identification Initiative To cite this cell line use: SK-PC-3 (RRID:CVCL_4055)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Doubling time: 59.5 hours (PubMed=7723277).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22585861

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S8209,10
D13S31711
D16S5399
TH018
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages http://dpsc.ccbr.utoronto.ca/cancer/get_cellline.pl?cellline=SK-PC-3
Publications

PubMed=8026879; DOI=10.1002/ijc.2910580207
Berrozpe G., Schaeffer J., Peinado M.A., Real F.X., Perucho M.
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.
Int. J. Cancer 58:185-191(1994)

PubMed=7723277
Vila M.R., Lloreta J., Schussler M.H., Berrozpe G., Welt S., Real F.X.
New pancreas cancers cell lines that represent distinct stages of ductal differentiation.
Lab. Invest. 72:395-404(1995)

PubMed=9665481; DOI=10.1016/S0002-9440(10)65561-7; PMCID=PMC1852940
Paciucci R., Vila M.R., Adell T., Diaz V.M., Tora M., Nakamura T., Real F.X.
Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met.
Am. J. Pathol. 153:201-212(1998)

PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396
Marcotte R., Brown K.R., Suarez Saiz F.J., Sayad A., Karamboulas K., Krzyzanowski P.M., Sircoulomb F., Medrano M., Fedyshyn Y., Koh J.L.-Y., van Dyk D., Fedyshyn B., Luhova M., Brito G.C., Vizeacoumar F.J., Vizeacoumar F.S., Datti A., Kasimer D., Buzina A., Mero P., Misquitta C., Normand J., Haider M., Ketela T., Wrana J.L., Rottapel R., Neel B.G., Moffat J.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Cancer Discov. 2:172-189(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4055
Encyclopedic resources Wikidata; Q54954517
Polymorphism and mutation databases Cosmic; 948729
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19