• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu258Lys (c.772G>A); ClinVar=VCV000012348; Zygosity=Unspecified (PubMed=8390283; PubMed=11992403).
  

PubMed=7214336
James George Rheinwald, Michael A. Beckett;
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.
Cancer Res. 41:1657-1663(1981)

PubMed=6722007; DOI=10.1038/bjc.1984.94; PMCID=PMC1976725
Ralph R. Weichselbaum, William K. Dahlberg, John Bertram Little, Thomas J. Ervin, Daniel Miller, Samuel Hellman, James George Rheinwald;
Cellular X-ray repair parameters of early passage squamous cell carcinoma lines derived from patients with known responses to radiotherapy.
Br. J. Cancer 49:595-601(1984)

PubMed=3458227; DOI=10.1073/pnas.83.8.2684; PMCID=PMC323364
Ralph R. Weichselbaum, William K. Dahlberg, Michael A. Beckett, Theodore Karrison, Daniel Miller, John Clark, Thomas J. Ervin;
Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.
Proc. Natl. Acad. Sci. U.S.A. 83:2684-2688(1986)

PubMed=3417487; DOI=10.1016/0360-3016(88)90297-0
Ralph R. Weichselbaum, Michael A. Beckett, Jeffrey L. Schwartz, Anatoly Dritschilo;
Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy.
Int. J. Radiat. Oncol. Biol. Phys. 15:575-579(1988)

PubMed=2573646; DOI=10.1080/09553008914551731
Ralph R. Weichselbaum, Jacob Rotmensch, Sijsan Ahmed-Swan, Michael A. Beckett;
Radiobiological characterization of 53 human tumor cell lines.
Int. J. Radiat. Biol. 56:553-560(1989)

PubMed=8390283; DOI=10.1038/bjc.1993.238; PMCID=PMC1968513
Julie E. Burns, M.C. Baird, Louise J. Clark, Philip A. Burns, Kirsten Gilian Edington, Charlotte Chapman, Roy Mitchell, Gordon Robertson, David Soutar, Eric Kenneth Parkinson;
Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines.
Br. J. Cancer 67:1274-1284(1993)

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=11992403; DOI=10.1002/ijc.10321
Susanne Popp, Stefan Waltering, Christel Herbst, Ingrid Moll, Petra Boukamp;
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas.
Int. J. Cancer 99:352-360(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=22546478; DOI=10.1016/j.ajpath.2012.02.028; PMCID=PMC3378915
Martin Degen, Easwar Natarajan, Patricia Barron, Hans R. Widlund, James George Rheinwald;
MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin gamma2 expression in oral dysplasia and squamous cell carcinoma.
Am. J. Pathol. 180:2462-2478(2012)

PubMed=22564525; DOI=10.1158/0008-5472.CAN-12-0423; PMCID=PMC3428932
Stephen J. Goldie, Klaas W. Mulder, David Wei-Min Tan, Scott K. Lyons, Andrew H. Sims, Fiona Mary Watt;
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.
Cancer Res. 72:3424-3436(2012)

PubMed=34435183; DOI=10.1016/j.mbplus.2021.100066; PMCID=PMC8377039
Bich Vu, Glauco R. Souza, Joern Dengjel;
Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome.
Matrix Biol. Plus 11:100066.1-100066.9(2021)

PubMed=34593609; DOI=10.1158/1541-7786.MCR-21-0306; PMCID=PMC10088464
Xi Chen, Gautam Adhikary, Suruchi Shrestha, Wen Xu, Jeffrey W. Keillor, Warren Naselsky, Richard L. Eckert;
Transglutaminase 2 maintains hepatocyte growth factor signaling to enhance the cancer cell phenotype.
Mol. Cancer Res. 19:2026-2035(2021)