ID   SCC-12F
AC   CVCL_4028
SY   SCC 12F; SCC 12-F; SCC12F; SSC12f
DR   cancercelllines; CVCL_4028
DR   Cosmic; 1608863
DR   Wikidata; Q54952330
RX   PubMed=9204953;
RX   PubMed=22006338;
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Leu; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val216Gly (c.647T>G); ClinVar=VCV000376671; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4026 ! SCC-12
SX   Male
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 13
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RX   PubMed=9204953; DOI=10.1111/1523-1747.ep12276459;
RA   Whitlow M.B., Klein L.M.;
RT   "Response of SCC-12F, a human squamous cell carcinoma cell line, to
RT   complement attack.";
RL   J. Invest. Dermatol. 109:39-45(1997).
//
RX   PubMed=22006338; DOI=10.1073/pnas.1114669108; PMCID=PMC3203814;
RA   Wang N.J., Sanborn Z., Arnett K.L., Bayston L.J., Liao W., Proby C.M.,
RA   Leigh I.M., Collisson E.A., Gordon P.B., Jakkula L.R., Pennypacker S.,
RA   Zou Y., Sharma M., North J.P., Vemula S.S., Mauro T.M., Neuhaus I.M.,
RA   LeBoit P.E., Hur J.S., Park K., Huh N., Kwok P.-Y., Arron S.T.,
RA   Massion P.P., Bale A.E., Haussler D., Cleaver J.E., Gray J.W.,
RA   Spellman P.T., South A.P., Aster J.C., Blacklow S.C., Cho R.J.;
RT   "Loss-of-function mutations in Notch receptors in cutaneous and lung
RT   squamous cell carcinoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:17761-17766(2011).
//