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Cellosaurus Mel249 (CVCL_3974)

[Text version]
Cell line name Mel249
Synonyms MEL249
Accession CVCL_3974
Resource Identification Initiative To cite this cell line use: Mel249 (RRID:CVCL_3974)
Comments Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:914; B2M; Simple; p.Asn62Argfs (c.184_185delAT); Zygosity=Unspecified (PubMed=16740750).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=16740750; DOI=10.1158/1078-0432.CCR-05-2174
Paschen A., Arens N., Sucker A., Greulich-Bode K.M., Fonsatti E., Gloghini A., Striegel S., Schwinn N., Carbone A., Hildenbrand R., Cerwenka A., Maio M., Schadendorf D.
The coincidence of chromosome 15 aberrations and beta2-microglobulin gene mutations is causative for the total loss of human leukocyte antigen class I expression in melanoma.
Clin. Cancer Res. 12:3297-3305(2006)

Cross-references
Anatomy/cell type resources BTO; BTO_0002952
Encyclopedic resources Wikidata; Q54905162
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number10