ID   NL20
AC   CVCL_3756
SY   NL-20
DR   CLO; CLO_0008179
DR   ATCC; CRL-2503
DR   BCRC; 60361
DR   BioSample; SAMN03471599
DR   BioSample; SAMN05292446
DR   GEO; GSM185872
DR   Wikidata; Q54930686
RX   PubMed=9216860;
RX   PubMed=1522038;
RX   PubMed=21566947;
WW   https://www.synapse.org/#!Synapse:syn31544547
CC   Population: Caucasian.
CC   Doubling time: ~48 hours (PubMed=1522038); ~24 hours (PBCF).
CC   Karyotypic information: 43,X,-X,-5,-7,-15,del(4)(p14),del(6)(q21-q25),i(14q),18p+,21p+,+i(5q),+der(15)t(7p;15q) (PubMed=1522038).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): ATCC=CRL-2503
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 12
ST   D18S51: 14
ST   D19S433: 13,15.2
ST   D21S11: 29,31.2
ST   D2S1338: 21,24
ST   D3S1358: 14,17
ST   D5S818: 12
ST   D7S820: 12
ST   D8S1179: 12,13
ST   FGA: 22
ST   Penta D: 9,11
ST   Penta E: 6,16
ST   TH01: 6,7
ST   TPOX: 9,11
ST   vWA: 14,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C5AZ ! NL20SV
SX   Female
AG   20Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 15
//
RX   PubMed=9216860; DOI=10.1159/000227713;
RA   Wittenkeller J.L., Storer B., Bittner G.N., Schiller J.H.;
RT   "Comparison of spontaneous and induced mutation rates in an
RT   immortalized human bronchial epithelial cell line and its tumorigenic
RT   derivative.";
RL   Oncology 54:335-341(1997).
//
RX   PubMed=1522038; DOI=10.1007/BF02634125;
RA   Schiller J.H., Bittner G.N., Oberley T.D., Kao C., Harris C.,
RA   Meisner L.F.;
RT   "Establishment and characterization of a SV40 T-antigen immortalized
RT   human bronchial epithelial cell line.";
RL   In Vitro Cell. Dev. Biol. Anim. 28:461-464(1992).
//
RX   PubMed=21566947; DOI=10.3892/ijo.4.2.461;
RA   Schiller J.H., Sabatini L., Bittner G.N., Pinkerman C.L., Mayotte J.,
RA   Levitt M.L., Meisner L.F.;
RT   "Phenotypic, molecular and genetic-characterization of transformed
RT   human bronchial epithelial-cell strains.";
RL   Int. J. Oncol. 4:461-470(1994).
//