Cellosaurus NK-92MI (CVCL_3755)
Cell line name | NK-92MI | ||||||||||||||||||||||||||||||||||||
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Synonyms | NK-92 MI; NK-92 mi; NK92-MI; NK92MI; NK-92 transfected with MFG-hIL2 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_3755 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: NK-92MI (RRID:CVCL_3755) | ||||||||||||||||||||||||||||||||||||
Comments | Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-6671. Population: Caucasian. Characteristics: No longer dependent on IL2. Microsatellite instability: Stable (MSS) (Sanger). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6001; IL2. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Caution: This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and non-commercial suppliers of NK-92MI. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: Natural killer cell; CL=CL_0000623. | ||||||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Natural killer cell lymphoblastic leukemia/lymphoma (NCIt: C82217) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_2142 (NK-92) Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 50Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=CRL-2408; CCRID=1102HUM-NIFDC00065; Cosmic-CLP=1330981 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=10365666; DOI=10.1089/10430349950018030 Patent=US8034332 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-2408
BCRC; 60438 - Discontinued KCB; KCB 200677YJ | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0008178
cancercelllines; CVCL_3755 CCRID; 1102HUM-NIFDC00065 Cell_Model_Passport; SIDM01201 Cosmic-CLP; 1330981 DepMap; ACH-002289 LINCS_LDP; LCL-1127 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | GDSC; 1330981
PharmacoDB; NK92MI_1160_2019 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54930658 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | GEO; GSM1670278 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 19-Dec-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 35 |