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Cellosaurus MLE-12 (CVCL_3751)

[Text version]
Cell line name MLE-12
Synonyms MLE 12; MLE12; Murine Lung Epithelial-12
Accession CVCL_3751
Resource Identification Initiative To cite this cell line use: MLE-12 (RRID:CVCL_3751)
Comments Doubling time: 7-9 hours (Note=At 12th passage) (PubMed=8248207).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB/N-Tg(SFTPC-TAg)5.1Jaw transgenic.
Sex of cell Female
Age at sampling 5M
Category Transformed cell line
Publications

PubMed=8248207; DOI=10.1073/pnas.90.23.11029; PMCID=PMC47915
Wikenheiser-Brokamp K.A., Vorbroker D.K., Rice W.R., Clark J.C., Bachurski C.J., Oie H.K., Whitsett J.A.
Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice.
Proc. Natl. Acad. Sci. U.S.A. 90:11029-11033(1993)

Cross-references
Cell line collections (Providers) ATCC; CRL-2110
Cell line databases/resources CLO; CLO_0007746
Anatomy/cell type resources BTO; BTO_0002268
Encyclopedic resources Wikidata; Q54905967
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16