Cellosaurus MCF-12A (CVCL_3744)
Cell line name | MCF-12A | ||||||||||||||||||
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Synonyms | MCF12A; Michigan Cancer Foundation-12A | ||||||||||||||||||
Accession | CVCL_3744 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: MCF-12A (RRID:CVCL_3744) | ||||||||||||||||||
Comments | Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: GrayJW breast cancer cell line panel. Part of: ICBP43 breast cancer cell line panel. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10782. Doubling time: 35.42 hours (GrayJW panel). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: Glycoproteome analysis by proteomics. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359. | ||||||||||||||||||
HLA typing | Source: PubMed=25960936
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Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Originate from same individual | CVCL_3745 ! MCF-12F | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 63Y | ||||||||||||||||||
Category | Spontaneously immortalized cell line | ||||||||||||||||||
STR profile | Source(s): ATCC Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://www.atcc.org/en/support/technical-support/faqs/normal-morphology-of-the-crl-10782-mcf-12a-cells https://lincs.hms.harvard.edu/resources/reagents/icbp43/ https://www.synapse.org/#!Synapse:syn2346643/wiki/62255 | ||||||||||||||||||
Publications | Patent=US5206165 PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008 PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004 PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020 PubMed=24162158; DOI=10.1007/s10549-013-2743-3 PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110 PubMed=25960936; DOI=10.4161/21624011.2014.954893 PubMed=28287265; DOI=10.1021/acs.jproteome.6b00470 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-10782 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007603
CLO; CLO_0037180 DepMap; ACH-002327 LINCS_HMS; 51089 LINCS_LDP; LCL-2082 TOKU-E; 2381 | ||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0002544 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03472816 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307365
ChEMBL-Targets; CHEMBL614322 PharmacoDB; MCF12A_894_2019 PubChem_Cell_line; CVCL_3744 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54904301 | ||||||||||||||||||
Experimental variables resources | EFO; EFO_0001202 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-TABM-157
ArrayExpress; E-TABM-244 GEO; GSM756372 GEO; GSM845396 GEO; GSM844585 GEO; GSM1053717 GEO; GSM1172975 GEO; GSM1172884 GEO; GSM1238117 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 1017163
Cosmic; 1136378 Cosmic; 1176637 Cosmic; 2560249 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD005339 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 05-Oct-2023 | ||||||||||||||||||
Version number | 29 |