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Cellosaurus McCoy (CVCL_3742)

[Text version]
Cell line name McCoy
Synonyms MCCOY; Mc Coy; McCoy B; McC
Accession CVCL_3742
Resource Identification Initiative To cite this cell line use: McCoy (RRID:CVCL_3742)
Comments Problematic cell line: Misidentified. Originally thought to be of human origin but found to be a mouse NCTC clone 929 derivative (PubMed=6451928; PubMed=20143388). Were thought to originate from the synovial fluid in the knee joint of a patient suffering from degenerative arthritis.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00079.
Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
Derived from site: In situ; Connective tissue; UBERON=UBERON_0002384.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/An.
Hierarchy Parent: CVCL_0462 (NCTC clone 929)
Sex of cell Male
Age at sampling 100D
Category Spontaneously immortalized cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=13531635; DOI=10.1007/BF00340146
Pomerat C.M., Kent S.P., Logie L.C.
Irradiation of cells in tissue culture. I. Giant cell induction in strain cultures versus elements from primary explants.
Z. Zellforsch. Mikrosk. Anat. 47:158-174(1957)

PubMed=4110420; DOI=10.1128/am.23.1.123-129.1972
Gordon F.B., Dressler H.R., Quan A.L., McQuilkin W.T., Thomas J.I.
Effect of ionizing irradiation on susceptibility of McCoy cell cultures to Chlamydia trachomatis.
Appl. Microbiol. 23:123-129(1972)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

PubMed=2754009; DOI=10.1128/jcm.27.6.1399-1400.1989
Thewessen E.A.P.M., Freundt I., van Rijsoort-Vos J.H., Stolz E., Michel M.F., Wagenvoort J.H.T.
Comparison of HeLa 229 and McCoy cell cultures for detection of Chlamydia trachomatis in clinical specimens.
J. Clin. Microbiol. 27:1399-1400(1989)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=33389257; DOI=10.1007/s10096-020-04106-0
Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)

Cell line collections (Providers) ATCC; CRL-1696
BCRC; 60064
BCRJ; 0160
ECACC; 90010305
NCBI_Iran; C123
Cell line databases/resources CLO; CLO_0007573
CLO; CLO_0007598
CLDB; cl3349
CLDB; cl3350
CLDB; cl3352
Biological sample resources BioSample; SAMN03151926
Encyclopedic resources Wikidata; Q54904270
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number23