Cellosaurus cell line IC-21 (CVCL

Cellosaurus IC-21 (CVCL_3726)

Cross-references
Cell line name	IC-21
Synonyms	IC21; TM; Transformed macrophage
Accession	CVCL_3726
Resource Identification Initiative	To cite this cell line use: IC-21 (RRID:CVCL_3726)
Comments	Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Peritoneum; UBERON=UBERON_0002358. Cell type: Peritoneal macrophage; CL=CL_0000581.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Web pages	https://www.atcc.org/en/support/technical-support/faqs/morphology-of-atcc-tib-186 https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html http://genepath.med.harvard.edu/bdlab/labprotocols/ic21.html
Publications	PubMed=4357034; DOI=10.3109/08820137309022816 Mocarelli P., Palmer J., Defendi V. A permanent line of macrophages with normal activity in a primary antibody response in vitro. Immunol. Commun. 2:441-447(1973) PubMed=1167563; DOI=10.4049/jimmunol.114.2_Part_2.765 Walker W.S., Demus A. Antibody-dependent cytolysis of chicken erythrocytes by an in vitro-established line of mouse peritoneal macrophages. J. Immunol. 114:765-769(1975) PubMed=1254971; DOI=10.4049/jimmunol.116.4.911 Walker W.S. Separate Fc-receptors for immunoglogulins IgG2a and IgG2b on an established cell line of mouse macrophages. J. Immunol. 116:911-914(1976)
Cell line collections (Providers)	ATCC; TIB-186
Cell line databases/resources	CLO; CLO_0004334 CLDB; cl1797
Anatomy/cell type resources	BTO; BTO_0000806
Encyclopedic resources	Wikidata; Q54897210
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	16