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Cellosaurus HS-5 (CVCL_3720)

[Text version]
Cell line name HS-5
Synonyms HS5
Accession CVCL_3720
Resource Identification Initiative To cite this cell line use: HS-5 (RRID:CVCL_3720)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11882.
Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Proteomics; Quantitative.
Derived from site: In situ; Bone marrow, stroma; UBERON=UBERON_0007195.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E3RF (HS5-CD40L)CVCL_E3RH (HS5-IL21)CVCL_E3RG (HS5-IL4)
Originate from same individual CVCL_0E35 ! HS-23
CVCL_0E34 ! HS-27
Sex of cell Male
Age at sampling 30Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3611; Technion Genomics Center

Markers:
AmelogeninX,Y
CSF1PO10,11
D1S165615,17.3
D2S44111
D2S133822,26
D3S135814,17
D5S81812
D7S82012
D8S117913,16
D10S124813,15
D12S39119,21
D13S31711
D16S53911
D18S5112,15
D19S43315
D21S1129,30
D22S104515,16
FGA21,24
Penta D10,13
Penta E5,6
TH017,9
TPOX8
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=7849321; DOI=10.1182/blood.V85.4.997.bloodjournal854997
Roecklein B.A., Torok-Storb B.
Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.
Blood 85:997-1005(1995)

Patent=US7129086
Torok-Storb B., Roecklein B.A., Johnson G.
Human marrow stromal cell lines which sustain hematopoiesis.
Patent number US7129086, 31-Oct-2006

Cross-references
Cell line collections (Providers) ATCC; CRL-3611
ATCC; CRL-11882 - Discontinued
NCBI_Iran; C626
Cell line databases/resources CLO; CLO_0004254
Anatomy/cell type resources BTO; BTO_0004123
Biological sample resources BioSample; SAMN03471343
ENCODE; ENCBS010ENC
Encyclopedic resources Wikidata; Q54896276
Experimental variables resources EFO; EFO_0005282
Proteomic databases PRIDE; PXD030239
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27