ID   BZR
AC   CVCL_3658
DR   CLO; CLO_0002067
DR   ATCC; CRL-9483
DR   Wikidata; Q54799725
RX   DOI=10.1007/978-1-4612-0411-4_25;
RX   Patent=US4885238;
RX   Patent=US5443954;
RX   PubMed=2539488;
RX   PubMed=2855021;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9483.
CC   Characteristics: Highly tumorigenic derivative of BEAS-2B.
CC   Transfected with: UniProtKB; P01115; Harvey murine sarcoma virus H-Ras (V-Ha-ras).
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 9,12
ST   D13S317: 13
ST   D16S539: 12
ST   D5S818: 12,13
ST   D7S820: 10,13
ST   TH01: 7,9.3
ST   TPOX: 6,11
ST   vWA: 17,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0168 ! BEAS-2B
SX   Male
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 17
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RX   DOI=10.1007/978-1-4612-0411-4_25;
RA   Lehman T.A., Harris C.C.;
RT   "Neoplastic transformation and suppression of transformation of human
RT   bronchial epithelial cells in vitro.";
RL   (In) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.251-258; Humana Press; New York (1990).
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RX   Patent=US4885238;
RA   Reddel R.R., Yang K., Rhim J.S., Brash D.E., Su R.T., Lechner J.F.,
RA   Gerwin B.I., Harris C.C., Amstad P.;
RT   "Immortalized human bronchial epithelial mesothelial cell lines.";
RL   Patent number US4885238, 05-Dec-1989.
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RX   Patent=US5443954;
RA   Reddel R.R., Yang K., Rhim J.S., Brash D.E., Su R.T., Lechner J.F.,
RA   Gerwin B.I., Harris C.C., Amstad P.;
RT   "Immortalized non-tumorigenic human bronchial epithelial cell lines.";
RL   Patent number US5443954, 22-Aug-1995.
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RX   PubMed=2539488; DOI=10.1093/jnci/81.8.587;
RA   Bonfil R.D., Reddel R.R., Ura H., Reich R., Fridman R., Harris C.C.,
RA   Klein-Szanto A.J.P.;
RT   "Invasive and metastatic potential of a v-Ha-ras-transformed human
RT   bronchial epithelial cell line.";
RL   J. Natl. Cancer Inst. 81:587-594(1989).
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RX   PubMed=2855021; DOI=10.1002/mc.2940010303;
RA   Amstad P., Reddel R.R., Pfeifer A.M.A., Malan-Shibley L.B.,
RA   Mark G.E. III, Harris C.C.;
RT   "Neoplastic transformation of a human bronchial epithelial cell line
RT   by a recombinant retrovirus encoding viral Harvey ras.";
RL   Mol. Carcinog. 1:151-160(1988).
//