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Cellosaurus SV7tert (CVCL_3602)

[Text version]
Cell line name SV7tert
Synonyms SV7 tert
Accession CVCL_3602
Resource Identification Initiative To cite this cell line use: SV7tert (RRID:CVCL_3602)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Kidney angiomyolipoma (NCIt: C3888)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_J654 (SV7)
Children:
CVCL_0F39 (SV7tert PDGF)
Sex of cell Female
Age at sampling 63Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2461

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,13
D7S82011
D13S3178
D16S5399,11
TH016,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=11485907; DOI=10.1016/S0002-9440(10)61720-8; PMCID=PMC1850536
Arbiser J.L., Yeung R.S.W., Weiss S.W., Arbiser Z.K., Amin M.B., Cohen C., Frank D.A., Mahajan S., Herron G.S., Yang J.-W., Onda H., Zhang H.B., Bai X.-H., Uhlmann E.J., Loehr A., Northrup H., Au P., Davis I.J., Fisher D.E., Gutmann D.H.
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
Am. J. Pathol. 159:483-491(2001)

PubMed=15509531; DOI=10.1016/S0002-9440(10)63418-9; PMCID=PMC1618658
Lu X.-J., Arbiser J.L., West J., Hoedt-Miller M., Sheridan A., Govindarajan B., Harral J.W., Rodman D.M., Fouty B.
Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells.
Am. J. Pathol. 165:1613-1620(2004)

PubMed=15695519; DOI=10.1074/jbc.M500411200
Govindarajan B., Shah A., Cohen C., Arnold R.S., Schechner J.S., Chung J., Mercurio A.M., Alani R.M., Ryu B., Fan C.-Y., Cuezva J.M., Martinez M., Arbiser J.L.
Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
J. Biol. Chem. 280:13936-13943(2005)

PubMed=17592550; DOI=10.2119/2006-00070.Lim; PMCID=PMC1892760
Lim S.D., Stallcup W.B., Lefkove B., Govindarajan B., Au K.S., Northrup H., Lang D., Fisher D.E., Patel A., Amin M.B., Arbiser J.L.
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Mol. Med. 13:160-165(2007)

Cross-references
Cell line collections (Providers) ATCC; CRL-2461 - Discontinued
Cell line databases/resources CLO; CLO_0009171
Anatomy/cell type resources BTO; BTO_0004390
Biological sample resources BioSample; SAMN03471581
Encyclopedic resources Wikidata; Q54970982
Polymorphism and mutation databases Cosmic; 2777739
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22