Cellosaurus LNZTA3WT11 (CVCL_3539)
| Cell line name | LNZTA3WT11 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | LNZTA3p53WT11; WT11 | ||||||||||||||||||
| Accession | CVCL_3539 | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: LNZTA3WT11 (RRID:CVCL_3539) | ||||||||||||||||||
| Comments | Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11544. Population: Caucasian. Characteristics: The expression of the luciferase reporter gene as well as the TP53 gene are under the control of a tetO operator. Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11998; TP53. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Brain, right parieto-occipital lobe. | ||||||||||||||||||
| Disease | Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94) | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0394 (LN-308) | ||||||||||||||||||
| Sex of cell | Male | ||||||||||||||||||
| Age at sampling | 60Y | ||||||||||||||||||
| Category | Cancer cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-11544 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Publications | Patent=US5807731 | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-11544 - Discontinued | ||||||||||||||||||
| Cell line databases/resources | CLO; CLO_0007370
LINCS_LDP; LCL-1355 | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q54902865 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 04-Apr-2012 | ||||||||||||||||||
| Last entry update | 10-Sep-2024 | ||||||||||||||||||
| Version number | 19 | ||||||||||||||||||